COVID-19, like other respiratory viruses, has extrapulmonary manifestations. In particular, exposure to the virus leads to damage to the cardiovascular system (CVS). The review presents the current problems of the combination of the new coronavirus infection COVID-19 and cardiovascular diseases. The results of a few clinical studies and individual clinical cases, illustrating the difficulties of managing patients with viral infection and comorbidities, are discussed. The combination of COVID-19 with cardiovascular diseases creates additional difficulties in diagnostics, determining priority tactics, changing the routing orders of patients with emergencies, and choosing therapy.